Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma
Duraj T, Kalamian M, Zuccoli G, Maroon JC, D’Agostino DP, et al.
Glioblastoma is the most aggressive primary brain tumor in adults, with a universally lethal prognosis despite maximal standard therapies. This consensus protocol targets the metabolic requirements of GBM cells for their two major fermentable fuels — glucose and glutamine.
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